Those are the ones who denied the messages of Jesus, Moses, Abraham, David, Solomon, Jacob, Noah, and of all the prophets (PBUT), and they will be punished by the Almighty in this life and the afterlife. We never see the punishment in this life but the punishment of the afterlife will be witnessed by all creatures.

( وَمَا لَهُم مِّن نَّاصِرِينَ … ) (…and they will have no helpers.): No one is a helpers, supporter or mediator except with the permission of the Almighty.